Regenflex

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In trauma-caused and degenerative diseases of the joints there is an in situ decrease of hyaluronic acid, due to which the synovial fluid is less viscous. Such deficiency determines a compression of the articular function and causes pain.

What is Hyaluronic Acid (HA) ?

  • It is a natural component of the connective tissue
  • Given its ability to form connections with collagen, proteoglycans, fibronectin and water, it is the basis of large molecular units that support the extracellular matrix.
  • It is an important component of the synovial fluid.
  • Helps to lubricate the joint and to damp down mechanical stress (lubricating and damping function)
  • Protects the cartilage against the penetration of inflammatory cells and from the lytic enzymes

Hyaluronic Acid and Joints

In trauma-caused and degenerative diseases of the joints there is an in situ decrease of hyaluronic acid, due to which the synovial fluid is less viscous. Such deficiency determines a compression of the articular function and causes pain.

THE INTRA-ARTICULAR ADMINISTRATION OF EXOGENOUS HYALURONIC ACID HELPS TO:

  • PREVENT THE NATURAL DEGRADING OF THE JOINTS
  • RSTORE THE VISCO-ELASTIC PROPERTIES OF THE SYNOVIAL FLUID
  • REDUCE THE PAIN AND INFLAMMATION
  • IMPROVE ARTICULAR MOBILITY
 
 

REGENFLEX 16mg/2ml

REGENFLEX is medical device based on a HIGHLY PURIFIED HYALURONIC ACID with a molecular weight between 800 an 1200 KDalton. The product are meant for injections and consist of a buffered physiological solution of Hyaluronic Acid sodium salt, which is the basic component of the synovial fluid and determines the visco-elastic properties of the latter.
The sodium hyaluronate used in REGENFLEX is obtained through fermentation thus, excluding any kind of chemical modification. This fact provides for a totally pure product, free of external residuals.
Each package contains one single-use glass syringe with 2ml of sterile solution.

REGENFLEX BIO-PLUS 75mg/3ml

Regenflex BIO-PLUS is a transparent gel based on cross-linked and linear intercalated Hyaluronic acid, created with an advanced and patented technological process. The aim of this intra-articular injectable is to prevent or to reduce pain, restoring the normal damping and lubricating function of the joint. Not only will the joint function improve, but the patient will also experience an improvement in their quality of life.
 

Causes of the chondral disease

In the case of chondral diseases, the bones, which in normal conditions should slide against each other without friction because of their smooth and flexible tissue, are instead impaired in the movements.

軟骨疾病的原因

全身或局部退化性軟骨病變

隨著年齡增長自然發生的關節退化,導致疼痛、關節活動受限,並降低生活質量;肥胖導致的超負荷也會造成關節提前出現退化性變。

創傷後軟骨疾病

關節的反覆創傷,比如膝關節,因某些運動(踢足球、打排球、打籃球、健美運動)或工作(磚匠、站立工作者、挖土機操作員等)導致膝蓋骨軟骨損傷,進而引發不同程度的疼痛和股四頭肌萎縮。

醫源性軟骨病變(使用非類固醇消炎藥或糖皮質激素導致)

在軟骨疾病的治療中使用抗炎藥物(非類固醇消炎藥或糖皮質激素)並沒有明確的證據支持。這些藥物毒性強,尤其對胃腸道的損傷極大。

正常狀態下軟骨組織柔軟且光滑,關節腔内的骨組織在彼此相互滑動時不會出現摩擦;在軟骨出現病狀的情况下,關節腔内的骨組織在運動時會出現組織損害。
這是由於關節滑液的流變性質發生了改變,導致滑液黏彈性明顯降低,進而出現下述情况:

預防和治療退化性和創傷後軟骨病變的使用方案。

根據有無疼痛/預防疼痛發生、以及修復創傷後或退化性軟骨病變等不同用途,推薦方案也有所差異。

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